In one of the biggest games of the weekend, the San Francisco 49ers and New Orleans Saints will go against each other in a battle of NFC teams. The San Francisco 49ers come into the game coming off a huge win on Monday Night Football over the Chicago Bears. The 49ers lead the Seattle Seahawks for first place in the NFC West. For New Orleans, they are looking to keep their hot streak going, as they have won four out of their last five games. The Saints are in third place in the NFC South, seeking a shot at a wildcard spot.

The New Orleans Saints are led by Drew Brees behind center. Brees is putting up great career numbers, as has not skipped a beat this season. The quarterback has thrown for over 3,000 yards and 28 touchdowns. The top receivers for the Saints are Marques Colston, with 7 touchdowns and Lance Moore, with 4. The Saints have won their last three home games following an 0-2 start the Dome.

The San Franscisco 49ers went into the home game against the Bears with a little frustration. The 49ers tied with St. Louis the previous week. San Francisco is playing back-up quarterback Collin Kaepernick. The former Nevada quarterback is in for Alex Smith, who was injured in the St. Louis game with a concussion. Frank Gore, the top running back for the 49ers has rushed for 831 yards and 5 touchdowns on the season. San Francisco is playing their first of two straight road games and four of their next five.

Odds and Sports Betting Line

• San Francisco 49ers pk
• New Orleans Saints pk

Free Prediction and Pick

The New Orleans Saints need a win in a bad way to stay alive in the postseason chase. For New Orleans, they would love a win to help their NFC West chances. The 49ers are the defending divisional champs. Look for the New Orleans offense to try to spread the San Francisco defense all over the field. Of course the Saints offense is what they rely on, while San Francisco is a big defensive team. We like offense to win in this one.

Prediction: New Orleans Saints 28-20

The New Orleans Saints and San Francisco 49ers are actually a pick’em in this game. That is a bit surprising, but oddsmakers are taking into account where the game is at, and that San Francisco is playing with a backup quarterback. For us, it doesn’t matter, the Saints are going to win this game at home. We are betting on the New Orleans Saints pk.

Pick: New Orleans Saints (pk)